As early as 1875, the Evangelistic Committee of the New Orleans Presbytery declared that missionary efforts were being expanded along the recently completed railroad line running north from New Orleans. So important was the railroad in new church development that all church work outside the city of New Orleans was described in relation to the nearest railroad. Points selected along the Illinois Central railroad line were Amite, Ponchatoula, Arcola, Tangipahoa, and Hammond.
The Ponchatoula Presbyterian Church, as it was then known, was organized on November 20, 1898. The church had many supply ministers during the early years, and the group of worshipers met in various locations until the first church building was bought. Services were held once a month on the second Sunday.
A wood frame church, constructed in 1892 and 1893 and used by the Methodists, stood near the corner of Fifth and Pine streets in Ponchatoula. In 1908, the Presbyterians purchased this building for $700 and moved it to Fourth Street. It is the oldest church building in Ponchatoula. The lot on Fourth Street was bought for $200, an organ for $100, and a violin for $15.
When the present brick sanctuary was constructed in 1963, the old church was moved to its present location behind the sanctuary. It has recently been renovated, and central heating and air conditioning has been added.
In February 1968, the church purchased an adjoining lot from the Lutherans for $15,000. It included the old Lutheran church and parsonage. The present education building was built in 1976 on the site of the parsonage. This structure includes a fellowship hall, a complete kitchen, a nursery, Sunday school classrooms, and restrooms.